Endocrinology & Metabolism Panel

Your Pathway to Proactive Health

Endocrinology & Metabolism Panel is a complex interplay of genetics, lifestyle, and environmental factors. While regular check-ups and healthy habits are essential, they may not provide a complete picture of your overall health risks and potential. The Endocrinology & Metabolism Panel delves deeper into your unique genetic profile, offering valuable insights into how your DNA shapes your susceptibility to certain conditions, response to exercise and diet, and overall well-being.

By identifying key genetic markers related to heart health, metabolic function, hormonal balance, and mental wellness, this panel equips you with practical information to make informed, personalized health decisions. Whether your goal is optimizing fitness, addressing hereditary health concerns, or implementing preventive strategies, this test provides a reliable foundation to take control of your health journey.

What the Panel Explores

40 Categories Covered

1. Allergies

Alcohol Aversion

Gluten Sensitivity

2. Amino acids

Glutamate Production

L-theanine

L-tyrosine

Serine Deficiency

3. Antioxidants / Supplements

Coenzyme Q10

Glutathione

Need for a diet rich in antioxidants

Probiotics

4. Behavioral Changes

Mood Disorder

5. Behaviors

Dopamine Levels

6. Benefit

Chamomile

S-adenosylmethionine (SAMe)

Stevia Sweetener Benefit

7. Cancer

Multiple Endocrine Neoplasm

Thyroid Neoplasm

8. Cardiovascular

Arginine-succinic aciduria

Familial Hyperlipoproteinemia Type III

Hereditary familial hypercholesterolemia

Hypercholesterolemia (Type B)

9. Cardiovascular and Cerebrovascular

Homocysteine Accumulation

Hypertension

Phospholipase Cg2 Defect

Sensitivity to Salt (Hypertension)

10. Diabetes

CAPN10

DPP-4

Diabetic Neuropathy

ENPP1

Early Type 2 Diabetes

Fasting Glucose Level Increase

Fasting Insulin

GLP-1

GLUT4

Glucose Intolerance

IRS-1

Insulin Sensitivity

Insulinogenic Index

Lower Insulin Secretion

MODY Type 1 Diabetes

11. Digestive system

Family diarrhea

Hyperglycinuria

Hyperlipoproteinemia

Peroxisomal Enzyme Deficiency

12. Drug Reactions

Better Response to Methotrexate

13. Endocrine system

Addison’s Disease

Autoimmune Thyroid Disease

Benefit of adopting a low glycemic index diet

Congenital Adrenal Hypoplasia (CAC)

Hashimoto’s Thyroiditis

Hyperparathyroidism

Hyperthyroidism

Hypophosphatemic Rickets

Hypothyroidism

Hypothyroidism (Goiter)

Monogenic Diabetes

Resistance to Thyroid Hormone

Severe Neonatal Hyperparathyroidism

Thyroid Orbitopathy (OT)

14. Essential Amino Acids

L-lysine

L-methionine

15. Fatty acids

Omega 6

Omega 9

16. General

Alcohol Intolerance

Aversion to Vegetables and Coffee

INSR

p70S6K

17. Genetic diseases

Alpha Antitrypsin Deficiency (AAT)

Alpha Hydroxyphenylpyruvate Hydroxylase Deficiency

Chitotrioidase Deficiency

Cholesterol Ester Transfer Protein Deficiency

Congenital Adrenal Hyperplasia (CAC)

Cytichrome-C Oxidase Deficiency

Deficiency of Tetrahydrobiopterin Synthesis

Dihydropyridine Dehydrogenase Deficiency

Familial Adenomatous Polyposis

Familial Glucocorticoid Deficiency (DFG)

Gamma-Glutamylcysteine Synthetase Deficiency

Glutathione S-transferase-1 Mutation

Glutathione Synthetase Deficiency

Lysosomal Acid Lipase Deficiency

Mevalonate Kinase Deficiency

18. Hematologic system

Albumin

Anemia

Aplastic anemia

Apolipoprotein E

Fanconi’s anemia

G6PD deficiency

HDL (Cholesterol)

HDL Deficiency (Family)

Hemolytic Anemia

High Ferritin

High ferritin (in men)

Hyperhomocysteinemia

Hyperinsulinemia

Hypoproteinemia

L-ferritin deficiency

19. Hereditary diseases

Lipotransferase 1 deficiency

20. Hormone

Acromegaly

Adiponectin Flag

Androstenedione

Anti-Müllerian hormone (AMH)

Change of Timo

Cushing’s Syndrome

Folic Acid Metabolism

Growth Hormone (GH) Deficiency

Leptin

Luteinizing Hormone (LH)

Reduction of Thyroid Hormonal Metabolism

Renina’s Greatest Activity

Resistin

SHBG levels

TSH

21. Hormones

5α-Reductase

Adiponectin Levels

Adrenal function

Adrenaline

Adrenocorticotrophic Hormone

Aromatase Deficiency

Benefit of Melatonin

Cortisol Level

DHEA/DHEAS

Estradiol

Estriol

Estrone

Excess of Aromatase

Growth Hormone Response

Impact of GH Replacement Treatment on Lipid Profile

22. Immune system

Autoimmune Disease

C3 (immune) deficiency

Crohn’s disease

Defect in Thyroid Hormonogenesis

Human Leukocyte Antigen (HLA)

Mannose Binding Protein Deficiency

23. Inflammations

Increased IL-6 with Vitamin E (Alpha-tocopherol) intake

Sjogren’s Syndrome

24. Metabolic

Ability to Digest Starch

Ability to digest starch

Ammonia and Glutamate Production

BCKDK gene

CBS Gene – Transsulfuration

Caffeine Metabolization

Carbohydrate Metabolism

Decline of NAD

Detox (Detoxification)

Detoxification

Glutamate to GABA Conversion

Gluten Intolerance

Glycation

Greater Insulin Sensitivity with Physical Exercise

HDL increase with Omega 6 intake

25. Metabolic disorders

3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency

3-Hydroxy-3-Methylglutaryl-CoA Synthetase 2 Deficiency

3-Hydroxyacyl-CoA Dehydrogenase Deficiency

Abetalipoproteinemia (Bassen-Kornzweig Syndrome)

Abetalipoproteinemia (Diet)

Adenosine Monophosphate Deaminase Deficiency

Alpha Methyl Acetoacetic Aciduria

Bile Acid Synthesis Deficiency

Brain Folate Transport Deficiency

Carnitine Acylcarnitine Translocase Deficiency

Carnitine Palmitoyltransferase I Deficiency

Carnitine Palmitoyltransferase II Deficiency

Cerebral Creatine Deficiency Syndrome

Cerebrotendinous Xanthomatosis

Congenital Sucrase Isomaltase Deficiency

26. Mitochondria

Oxidative Phosphorylation

27. Need for Nutrients

Apigenin need

Benefit of Bergamot

Betaine

Bromelain

Calcium

Choline

Chrome

Copper

Hop

Iodine

Iron

Lutein

Lycopene

Magnesium

Manganese

28. Neurodegenerative diseases

Peripheral neuropathy

29. Oxidation

Antioxidant Capacity

Glutamic Acid Metabolism

Individuals not expressing CYP3A5

Oxidative stress

30. Personal characteristics

Alcohol Metabolism

Greater Stimulus with Caffeine

Hypersensitivity to Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Increased Probability of Fatigue

Mitochondrial Energy Production

Pineal Hyperplasia

Spondyloepiphyseal Dysplasia

31. Psychiatric

Anorexia Nervosa

32. Reactions to Treatments

Levothyroxine Combination therapy with Liothyronine

33. Reproductive system

Age at Menarche

Gestational diabetes

Polycystic Ovary Syndrome

34. Skeletal system (bones)

Development Defects

Risk of amputation in case of diabetic foot ulcer

35. Skin

Elastin Deficiency

36. Urinary system

Uric Acid (Concentration)

37. Vision (Ophthalmology)

Diabetic retinopathy

38. Vitamins

Folate

Vitamin A

Vitamin B12

Vitamin B2

Vitamin B6

Vitamin B7 (Biotin)

Vitamin B9 (Folic Acid)

Vitamin C

Vitamin D

Vitamin E

Vitamin K

39. Vitamins need

Reduced Conversion of Beta Carotene to Retinol

Riboflavin Deficiency

40. Weight

Absorption of Fats

Benefit of Physical Exercise for Weight Loss

Fat Metabolism

Fibers and slimming

Ghrelin

Greater Resistance to Weight Loss on Low Calorie Diets

High Levels of Fatty Acids after Fat Ingestion

Increased waist measurement with the habit of smoking a lot

Intake of saturated fat and increased body fat

Irisina

Lower Use of Glucose after Carbohydrate Ingestion

Lower Weight Gain on High Fat Diets

Obesity (monogenic)

Obesity in Adolescents

Preference for bitter foods

Why Choose Us?

After analyzing genetic data, HealthCentric provides actionable lifestyle
recommendations, including diet, exercise, and sleep.

Customized Diet Plans

Nutrition strategies tailored to genetic requirements.

Personalized Fitness Regimens

Exercise plans aligned with genetic predispositions.

Supplement Guidance

Expert recommendations to optimize health and address deficiencies.

Ongoing Support

Continuous consultations to adjust plans as health needs evolve.